Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA27759 | CA64169 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+LPV+TDF | 104 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46MIL, I47A, V82A, L90M | L33F | L10IT, I13V, M36I, R41RK, L63P, K70E, A71V, I93L |
| >CA64169| codons 1-99 PQITLWQRPTVTVKIGGQLKEALLDTGADDTIFEEINLPGKWKPKLAGGIGGFIKVRQYD QIPIEICGHEVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215Y | K219E | Y188L | K101H | P4T, V60I, S68G, T69TI, V106VI, K122E, I135V, S162C, V179I, T200A, E203D, L228H, P243PH, V245E, K277R, Q278H, E297K |
| >CA64170| codons 1-305 PISTIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKNGIRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSITVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII YQYVDDLLVGSDLEIGQHRAKIDELRQHLLRWGFYTPDEKHQKEPPFHWMGYELHPDKWT VQHIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGTKALTEVIPLTKEAE LELAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |