Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA22088 | CA64070 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | 4 |
| 2 | None | 24 |
| 3 | 3TC+DDI+TDF | 78 |
| 4 | ABC+DDI+EFV | 87 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | K103N, Y181C, M230L | V35VI, S68N, T69S, V90I, K101KR, V106I, D177E, V179VL, Q207KR, R211Q, H221Y, A272P, V292I, I293V, P294S, E297K |
| >CA64070| codons 1-305 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKRKDNSKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLRKNKSITVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEILI CQYMDDLYVGSDLEIGQHRTKIEELRRHLLQWGFTTPDKKYQKEPPFLWLGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVSLTKEAE LELAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, N37D, K43R, R57K, L63P, A71T, I93L |
| >CA64069| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMDLPGRWRPKMIGGIGGFIKVKQYD QIPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |