Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14311 | CA64023 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 169 |
| 2 | 3TC+D4T+NVP | 96 |
| 3 | 3TC+APV+D4T | 130 |
| 4 | 3TC+APV+D4T+DDC | 43 |
| 5 | 3TC+APV+D4T+DDC+RTV | 22 |
| 6 | 3TC+APV+D4T+DDC | 61 |
| 7 | ATV+D4T+DDC+RTV | 26 |
| 8 | 3TC+APV+DDI+LPV+TDF | 35 |
| 9 | 3TC+DDI+FPV+LPV+TDF | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46IV, I47V, I54M, I84V, L90M | L10F, V11I, G73T, L89V | I13V, L19Q, K20M, L33V, E35A, M36I, R57K, I62V, L63P, I64V, T74A |
| >CA64023| codons 1-99 PQITLWQRPFITVKIGGQQMEALLDTGADDTIVEAINLPGRWKPKVVGGIGGFMKVKQYD QVPVEICGHKAITAVLVGPTPVNVIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69DE, K70RS, L74LV, M184V, T215F | D67G, K219Q | Y181C, G190A | E6D, V35VI, S68SG, K101Q, K102R, L109LI, K122E, I135T, I142V, T200TA, Q207R, R211Q, D218E, L228H, R284K, I293V, E297V |
| >CA64024| codons 1-301 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKGGESWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQRKKSVTVIDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYVDDLYVASDLEIGQHRAKIEELRRHLLQWGFFTPEQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKALTEVVPLTVEAE L |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |