Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8386 | CA63933 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 9 |
| 2 | 3TC+D4T+NFV | 260 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, L90M | T12S, I13V, I15V, L19I, K20T, M36I, R41RK, K55KR, R57RK, D60E, I62V, L63P, I64V, I93IL |
| >CA63933| codons 1-99 PQITLWQRPLVSVKVGGQITEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIRVKQYE QVPVEICGHKAIGTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K11T, K20R, K22R, V60I, D123E, I135L, K166R, D177E, T200I, A272P, V276VI, I293V, E297A |
| >CA63934| codons 1-301 PISPIETVPVTLKPGMDGPRVRQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRIKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGTKALTEVVPLTAEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease mutations and protease inhibitor cross resistance. | AAC, 2010 |