Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1524 | CA63895 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 17 |
| 2 | AZT+DDI | 13 |
| 3 | None | 122 |
| 4 | 3TC+AZT | 35 |
| 5 | 3TC+D4T | 78 |
| 6 | 3TC+D4T+SQV | 20 |
| 7 | 3TC+D4T+RTV+SQV | 274 |
| 8 | 3TC+APV+LPV+TDF | 135 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48M, I54V, V82A, I84V | F53L | L10I, V11L, I13V, K14KR, A22V, E35D, M36I, N37D, I62V, L63P, A71V, T74S, T91S, Q92K |
| >CA63895| codons 1-99 PQITLWQRPILTVRIGGQLKEVLLDTGADDTVLEDIDLPGRWKPKMIMGIGGLVKVRQYD QVPIEICGHKVIGSVLVGPTPANVIGRNLLSKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, M184V, L210W, T215Y | F77L | E138K | V35T, T39E, E44D, V60I, V118I, K122E, D123N, I135T, S162X, H208Y, R211K, V245VE, A272P, K277R, T286A, E297A |
| >CA63896| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKDGKISKIGPENPYNTPI FAIKKKNSDKWRKLMDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSTNNKTPGIRYQYNVLPQGWKGSPAIFQXSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTAEAE L |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D3DE, S17N, L28I, S39C, I72V, L101I, F181L, T206S |
| >CA158563| codons 1-288 FLEGIDKAQEEHEKYHNNWRAMASDFNIPPVVAKEIVACCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGSN FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV LIHNFKRKGGIGGYSAGERIVDIIASDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |