Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| NV_LBIST052 | LBIST052 | DRC | 2002 | HIV1 | G | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, M36I, R41K, L63P, C67E, H69K, V82I, L89M |
| >LBIST052| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39R, V60I, K64R, K122E, D123G, S162C, K173T, Q174R, I195L, G196E, T200A, Q207E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T377L, S379C, T386I, Q394R, E396D, A400V, Q428R, K431T, V435P |
| >LBIST052| codons 1-438 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPI FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTRNPDIVI YQYMDDLYVGSDLELEQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE MELAENREILKEPVHGVYYDPSKELIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVKQLTEVVQKIALECIVIWGKIPKFKLPIRKDTWEVWWTEYWQATWIPEWEFVNTP PLVKLWYRLETEPIPGAE |
References
| Author | Title | Citation |
| Vidal, N | HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC). | ARHR, 2006 |