<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NV_KTB242 02.KTB242 DRC 2002 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, G16E, K20R, E35D, M36I, R41K, K45R, L63A, H69K, L89M, I93L  
>02.KTB242| codons 1-99
PQITLWQRPLVTIKVEGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QIAIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39R, S48T, V60I, K122E, D123N, I135T, K173S, Q174K, D177E, G196E, T200A, I202V, Q207A, R211S, V245I, D250E, S251H, A272S, T286A, E291D, V292I, I293V, P294T, E297A, V314A, D324E, Q334S, G335D, R356T, M357R, R358K, G359S, T377R, T386I, K390R, E399D, E404D, E413D  
>02.KTB242| codons 1-434
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICREMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI
YQYMDDLYVGSDLEIEQHRAKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIILPEKEHWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVTLTAEAE
LELAENREILKEPAHGVYYDPSKELIAEIQKQGSDQWTYQIYQEPFKNLKTGKYATRKSA
HTNDVKQLTEAVQKIARESIVIWGKIPKFRLPIQKETWDAWWTDYWQATWIPDWEFVNTP
PLVKLWYQLEKEPI

References
Author Title Citation
Vidal, N HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC). ARHR, 2006