<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NV_KS072 02.KS072 DRC 2002 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16E, K20R, E35D, M36I, P39S, R41K, K45R, I62V, L63T, E65D, H69K, I72T, L89M  
>02.KS072| codons 1-99
PQITLWQRPLVTIKIEGQLREALLDTGADDTVLEDINLSGKWKPRMIGGIGGFIKVRQYD
QVTIDICGKKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39K, K43A, V60I, D123E, I135V, K173L, Q174K, D177E, Q197E, T200I, Q207D, R211K, V245Q, E248D, S251N, K281R, T286A, E291D, V292I, I293V, E297R, E312D, R356K, M357R, R358K, G359S, E370D, A371V, I375V, A376V, T377M, E399D, T403M, K431T  
>02.KS072| codons 1-438
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEAEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIVI
YQYMDDLYVGSDLEIGEHRIKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDNWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTREAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKRKSA
HTNDVKQLTDVVQKVVMESIVIWGKTPKFKLPIQKETWDAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIVGAE

References
Author Title Citation
Vidal, N HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC). ARHR, 2006