<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NV_KP122 02.KP122 DRC 2002 HIV1 G PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, K20I, E35Q, M36I, R41K, L63P, C67E, H69K, V82I, L89M  
>02.KP122| codons 1-99
PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, K122E, I135V, K173T, Q174K, T200A, Q207A, R211K, V245Q, E248D, D250E, A272S, K281R, E291D, V292I, I293V, E297A, I326T, I329V, Q334H, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T386L, K390R, Q394R, E396D, A400V, E413D, Q428R, K431T, V435P  
>02.KP122| codons 1-439
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCRLLRGTKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLTAEVQKQGHDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEVVQKIATESIVIWGKLPKFRLPIRKDTWEVWWTEYWQATWIPDWEFVNTP
PLVKLWYRLETEPIPGAET

References
Author Title Citation
Vidal, N HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC). ARHR, 2006