Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| NV_KP009 | 02.KP009 | DRC | 2002 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35N, M36L, R41K, L63P, H69K, V82I, L89M |
| >02.KP009| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLENLNLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60I, D121H, K122E, T139K, A158S, S162A, D177E, I178M, T200A, Q207A, R211K, V245Q, L246I, E248D, D250E, I257V, A272P, T286A, E291Q, I293V, P294E, E297K, S322A, Q334H, G335D, R356K, M357R, R358G, G359A, K366R, T369A, I375V, W383F, T386I, Q394R, A400I, E404D, Q428R, K431T, V435P, A437V, F440Y |
| >02.KP009| codons 1-440 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQIPDKESWTVNDVQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTQVVELTKEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRGAA HTNDVRQLAEAVQKVATESIVIFGKIPKFKLPIRKETWEIWWTDYWQATWIPEWEFVNTP PLVKLWYRLETEPIPGVETY |
References
| Author | Title | Citation |
| Vidal, N | HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC). | ARHR, 2006 |