<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NV_KP009 02.KP009 DRC 2002 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35N, M36L, R41K, L63P, H69K, V82I, L89M  
>02.KP009| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLENLNLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, D121H, K122E, T139K, A158S, S162A, D177E, I178M, T200A, Q207A, R211K, V245Q, L246I, E248D, D250E, I257V, A272P, T286A, E291Q, I293V, P294E, E297K, S322A, Q334H, G335D, R356K, M357R, R358G, G359A, K366R, T369A, I375V, W383F, T386I, Q394R, A400I, E404D, Q428R, K431T, V435P, A437V, F440Y  
>02.KP009| codons 1-440
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQIPDKESWTVNDVQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTQVVELTKEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRGAA
HTNDVRQLAEAVQKVATESIVIFGKIPKFKLPIRKETWEIWWTDYWQATWIPEWEFVNTP
PLVKLWYRLETEPIPGVETY

References
Author Title Citation
Vidal, N HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC). ARHR, 2006