Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG96 | 96_w27 | U.K. | 1999 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | ABC+AZT | 27 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20R, M36I, N37ND, R41K, H69K, L89M |
| >96_w27| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, V35T, V60I, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, E203D, Q207E, P243H, V245E, K281R, T286A, E291D, V292I, I293V, S322T, G335D, Y339F, R356K, M357K, G359S, T369TA, A371V, I375V, A376S, T377TI, K390R |
| >96_w27| codons 1-400 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEMVI YQYMDDLYVGSDLEIGQHRAKIDELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQHIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTFQIYQEPFKNLKTGKYAKKRSA HTNDVKQLAEVVQKVSIESIVIWGKTPKFRLPIQKETWEA |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |