<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DMG90 90_w-6 U.K. 1998 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L10LF I13V, I15IV, E35D, M36I, R41K, I64V, E65D  
>90_w-6| codons 1-99
PQITLWQRPFVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILVDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K22R, V35T, K49R, V60I, V106I, K122E, D123DN, I135T, I142V, D177E, I178M, I195L, T200I, Q207G, R211K, V245K, A272P, L282C, T286A, I293V, S322T, A327AV, G335GD, P345Q, F346Y, R356K, M357S, A360T, E370A, A376AT, T377Q, S379SC, T386I, K390R, Q394QL, E399D  
>90_w-6| codons 1-399
PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLELGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKCLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLIVEIQKQGQDQWTYQIYQEQYKNLKTGKYAKSRGT
HTNDVKQLTAAVQKITQECIVIWGKIPKFRLPILKETWD

References
Author Title Citation
Gibb, DM Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). Antivir Ther, 2002