Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG90 | 90_w-4 | U.K. | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15IV, N37D, R41K, D60E, L63LS, I64V, V77I |
| >90_w-4| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEEMDLPGKWKPKMIGGIGGFIKVRQYE QISVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39TA, V60I, T107TS, K122E, D123N, D177E, I178M, T200M, Q207E, R211K, V245E, D250E, K277R, T286A, P294AV, E312N, G335D, P345Q, F346H, R356K, M357R, A360T, T377LQ, S379SC, K390R, Q394T, E399D | F130FL |
| >90_w-4| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVLDVGDAYFSVPL DENFRKYTALTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRMKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVIVLTEEAE LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQHKNLKTGKYAKRRGT HTNDVKQLTEAVQKIAQECIVIWGKTPKFRLPITKETWDA |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |