<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DMG90 90_w-4 U.K. 1998 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15IV, N37D, R41K, D60E, L63LS, I64V, V77I  
>90_w-4| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEEMDLPGKWKPKMIGGIGGFIKVRQYE
QISVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39TA, V60I, T107TS, K122E, D123N, D177E, I178M, T200M, Q207E, R211K, V245E, D250E, K277R, T286A, P294AV, E312N, G335D, P345Q, F346H, R356K, M357R, A360T, T377LQ, S379SC, K390R, Q394T, E399D F130FL
>90_w-4| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVLDVGDAYFSVPL
DENFRKYTALTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIGQHRMKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVIVLTEEAE
LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQHKNLKTGKYAKRRGT
HTNDVKQLTEAVQKIAQECIVIWGKTPKFRLPITKETWDA

References
Author Title Citation
Gibb, DM Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). Antivir Ther, 2002