Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG40 | 40_w0 | U.K. | 1998 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LI, I15V, K20KR, E35D, M36I, R41K, R57K, Q61DN, L63LCFR, I93L |
| >40_w0| codons 1-99 PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD NIRIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60I, D123E, E138EA, I142IT, S162C, E169D, K173T, Q174K, I178L, V179VI, T200TA, Q207D, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, P294S, E297A, V317VA, I329V, Q334H, R356K, G359S, A376S, T377Q, Q394L, E399D |
| >40_w0| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSPAIFQCSMTKILDPFRTKNPDLII YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVSLTAEAE LELAENREILKEPVHGAYYDPSKDLIAEVQKQGHGQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKISQESIVIWGKTPKFKLPILKETWD |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |