<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DMG40 40_w0 U.K. 1998 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, I15V, K20KR, E35D, M36I, R41K, R57K, Q61DN, L63LCFR, I93L  
>40_w0| codons 1-99
PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NIRIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, D123E, E138EA, I142IT, S162C, E169D, K173T, Q174K, I178L, V179VI, T200TA, Q207D, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, P294S, E297A, V317VA, I329V, Q334H, R356K, G359S, A376S, T377Q, Q394L, E399D  
>40_w0| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSPAIFQCSMTKILDPFRTKNPDLII
YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVSLTAEAE
LELAENREILKEPVHGAYYDPSKDLIAEVQKQGHGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKISQESIVIWGKTPKFKLPILKETWD

References
Author Title Citation
Gibb, DM Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). Antivir Ther, 2002