<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DMG36 36_w8 U.K. 1998 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 8

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49KR, K104KR, K122KE, D123DN, S162C, E169D, K173A, Q174K, T200TAIV, Q207AD, R211K, V245Q, E248D, A272P, T286V, E291D, V292I, I293V, E297V, V317VA, I329V, G333E, G359S, T377L, K390R, E399D  
>36_w8| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRVKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTDIVPLTVEAE
LELAENREILKEPVHGAYYDPSKDLIAEVQKQEQGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G17E, E35D, M36I, R57K, Q61N, L63T, E65ED, I72T, L89M  
>36_w8| codons 1-99
PQITLWQRPLVTIKIGEQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
NITIDICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Gibb, DM Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). Antivir Ther, 2002