Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG27 | 27_w0 | U.K. | 1999 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, I15IV, G16GE, G17GE, L19IT, K20KR, E35D, M36I, R41K, R57K, L63T, E65D, I72IT, L89M |
| >27_w0| codons 1-99 PQITLWQRPLVSIKVEEQTREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QITIDICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39A, E40ED, F87L, D123E, I135L, S162H, K173T, Q174K, I195L, T200A, Q207AE, R211K, V245Q, E248D, A272P, E291D, V292I, I293V, P294T, E297A, S322A, P345T, R356K, G359S, T377M, S379C |
| >27_w0| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDLWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRTKNPDIVI YQYMDDLYVGSDLELGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVTLTAEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQGQWTYQIYQETFKNLKTGKYAKMRSA HTNDVKQLTEAVQKIAMECIVIWGKTPKFKLPIQKETWEA |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |