Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG18 | 18_w0 | U.K. | 1999 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, R41K, I64V, V77I |
| >18_w0| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75I | V35E, K49R, V60I, D121Y, K122E, I132L, K166R, D177E, I178M, T200I, Q207E, R211K, I244V, V245T, D250E, A272S, K277R, L282C, T286A, E297K, I326T, R356K, A360T, T377Q, T386I, K390R |
| >18_w0| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPVTLPEKESWTVNDIQKLVGKLNWASQIYSGIKVRQLCKCLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLTAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRGT HTNDVKQLTEAVQKIAQESIVIWGKIPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |