Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG112 | 112_w-38 | U.K. | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| R41K, I62IV, L63P, C67CS, V77VI |
| >112_w-38| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QVPIEISGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39D, K49KR, V60I, K102KQ, K122E, I135T, D177E, I178M, V179VG, T200A, Q207E, R211K, V245M, D250E, A272P, T286A, E297K, Q334HN, G335D, R356K, M357MT, A360AT, K366KR, I375IV, T377L, S379SG, T386I, K390R |
| >112_w-38| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMGI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKTRGT HTNDVRQLTEAVQKVALEGIVIWGKIPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |