<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-A ptAW24 U.S. 1995 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 24

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T, I84V   L10R, T12A, R57K, L63P, I64V  
>ptAW24| 11 | codons 1-99 | clone 11
PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW24| 10 | codons 1-99 | clone 10
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVKQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF
>ptAW24| 9 | codons 1-99 | clone 9
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVKQYD
QILVEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF
>ptAW24| 8 | codons 1-99 | clone 8
PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW24| 7 | codons 1-99 | clone 7
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF
>ptAW24| 6 | codons 1-99 | clone 6
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF
>ptAW24| 5 | codons 1-99 | clone 5
PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF
>ptAW24| 4 | codons 1-99 | clone 4
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVKQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF
>ptAW24| 3 | codons 1-99 | clone 3
PQITLWQRPRVTIKMGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF
>ptAW24| 2 | codons 1-99 | clone 2
PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIRVKQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF
>ptAW24| 1 | codons 1-99 | clone 1
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPTNVIGRSLLTQIGCTLNF
>ptAW24| codons 1-99
PQITLWQRPRVAIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QIPVEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005