Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-A | ptAW24 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 24 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82T, I84V | L10R, T12A, R57K, L63P, I64V |
| >ptAW24| 11 | codons 1-99 | clone 11 PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW24| 10 | codons 1-99 | clone 10 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVKQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW24| 9 | codons 1-99 | clone 9 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVKQYD QILVEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF >ptAW24| 8 | codons 1-99 | clone 8 PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW24| 7 | codons 1-99 | clone 7 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW24| 6 | codons 1-99 | clone 6 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF >ptAW24| 5 | codons 1-99 | clone 5 PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF >ptAW24| 4 | codons 1-99 | clone 4 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVKQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW24| 3 | codons 1-99 | clone 3 PQITLWQRPRVTIKMGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW24| 2 | codons 1-99 | clone 2 PQITLWQRPVVAIKIGGQLKKALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIRVKQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW24| 1 | codons 1-99 | clone 1 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPTNVIGRSLLTQIGCTLNF >ptAW24| codons 1-99 PQITLWQRPRVAIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QIPVEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |