<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DMG107 107_w-9 U.K. 1998 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, T12S, I13V, L19LS, K20I, E35D, M36I, I64IM, H69K, K70KR, V82I, L89M  
>107_w-9| codons 1-99
PQITLWQRPIVSVKIGGQSIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD
QILMEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        P4H, E6D, V35T, T39AE, I50IV, K122E, D123DG, I142V, K173S, Q174K, D177E, I178IM, T200A, Q207A, R211S, V245E, K281R, T286A, E291D, V292I, I293V, E297R, A304E, E312N, D324E, G335D, R356K, M357K, G359S, A360T, T369A, T377M, K390R  
>107_w-9| codons 1-399
PISHIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKVGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTREAE
LELEENREILKNPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRST
HTNDVKQLAEAVQKIAMESIVIWGKTPKFRLPIQKETWE

References
Author Title Citation
Gibb, DM Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). Antivir Ther, 2002