Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DMG107 | 107_w-9 | U.K. | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LI, T12S, I13V, L19LS, K20I, E35D, M36I, I64IM, H69K, K70KR, V82I, L89M |
| >107_w-9| codons 1-99 PQITLWQRPIVSVKIGGQSIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QILMEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4H, E6D, V35T, T39AE, I50IV, K122E, D123DG, I142V, K173S, Q174K, D177E, I178IM, T200A, Q207A, R211S, V245E, K281R, T286A, E291D, V292I, I293V, E297R, A304E, E312N, D324E, G335D, R356K, M357K, G359S, A360T, T369A, T377M, K390R |
| >107_w-9| codons 1-399 PISHIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKVGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTREAE LELEENREILKNPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRST HTNDVKQLAEAVQKIAMESIVIWGKTPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Gibb, DM | Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). | Antivir Ther, 2002 |