<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DMG102 102_w51 U.K. 1999 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ABC+NFV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V32L I13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, L89M  
>102_w51| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTLLEDINLPGKWKPRMIGGIGGFIKVKQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11KT, K20R, V35T, T39KQ, E40D, K122E, D123N, E138EA, K173S, T200A, Q207AD, F214L, V245Q, E248D, A272P, T286A, E291ED, V292VI, I293V, P294PST, K311R, G335D, M357K, G359S, T369A, A371V, A376V, T377M, K390R  
>102_w51| codons 1-399
PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICQDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRDHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVKQLAEVVQKIVMESIVIWGKTPKFRLPIQKETWE

References
Author Title Citation
Gibb, DM Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial). Antivir Ther, 2002