<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-B ptBW52 U.S. 1996 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A L24I L10I, K20M, E35D, M36I, R41K, L63P, A71V  
>ptBW52| 9 | codons 1-99 | clone 9
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| 8 | codons 1-99 | clone 8
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| 7 | codons 1-99 | clone 7
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| 6 | codons 1-99 | clone 6
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD
QIPIEIRGHKVIGTVLVGPTPANLIGRNFLTQIGCTLNF
>ptBW52| 5 | codons 1-99 | clone 5
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGMDGPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| 4 | codons 1-99 | clone 4
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| 2 | codons 1-99 | clone 2
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| 1 | codons 1-99 | clone 1
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptBW52| codons 1-99
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005