<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-C ptCW44 U.S. 1996 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 44

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, V82A   L63A, I64M, A71V, I72V, Q92R  
>ptCW44| 8 | codons 1-99 | clone 8
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptCW44| 7 | codons 1-99 | clone 7
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIAIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptCW44| 6 | codons 1-99 | clone 6
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMCLPGRWKPKIIGGIGGFIKVRQYD
QVSIEICGHKAIGTVLIGPTPVNIVGRNLLTQLGCTLNF
>ptCW44| 5 | codons 1-99 | clone 5
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIPMEICGHKVVGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptCW44| 4 | codons 1-99 | clone 4
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIPMEICGHKVVGTVLVGPTPANIIGRNLLTRIGCTLNF
>ptCW44| 3 | codons 1-99 | clone 3
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIPMEICGHKVVGTVLVGPTPANIIGRNLLTRIGCTLNF
>ptCW44| 2 | codons 1-99 | clone 2
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIAIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF
>ptCW44| 1 | codons 1-99 | clone 1
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIPMEICGHKVVGTVLVGPTPANIIGRNLMTQIGCTLNF
>ptCW44| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIIGGIGGFIKVRQYD
QIAMEICGHKVVGTVLVGPTPANIIGRNLLTRIGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005