Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-A | ptAW12 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 12 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | L10R, R57K, I64V |
| >ptAW12| 12 | codons 1-99 | clone 12 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 11 | codons 1-99 | clone 11 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 10 | codons 1-99 | clone 10 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 9 | codons 1-99 | clone 9 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 8 | codons 1-99 | clone 8 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 7 | codons 1-99 | clone 7 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 6 | codons 1-99 | clone 6 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 5 | codons 1-99 | clone 5 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGKNLLTQIGCTLNF >ptAW12| 4 | codons 1-99 | clone 4 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 3 | codons 1-99 | clone 3 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| 2 | codons 1-99 | clone 2 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILXEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >ptAW12| codons 1-99 PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |