<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-A ptAW12 U.S. 1995 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I   L10R, R57K, I64V  
>ptAW12| 12 | codons 1-99 | clone 12
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 11 | codons 1-99 | clone 11
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 10 | codons 1-99 | clone 10
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 9 | codons 1-99 | clone 9
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 8 | codons 1-99 | clone 8
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 7 | codons 1-99 | clone 7
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 6 | codons 1-99 | clone 6
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 5 | codons 1-99 | clone 5
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGKNLLTQIGCTLNF
>ptAW12| 4 | codons 1-99 | clone 4
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 3 | codons 1-99 | clone 3
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| 2 | codons 1-99 | clone 2
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILXEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
>ptAW12| codons 1-99
PQITLWQRPRVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD
QILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005