Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6361 | CA59608 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 87 |
| 2 | AZT+DDI | 30 |
| 3 | 3TC+AZT+IDV | 205 |
| 4 | 3TC+ABC+AZT+IDV | 43 |
| 5 | ABC+D4T+RTV+SQV | 243 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | V11I, N88T | L10I, I15V, Q18H, L19I, K20I, M36I, N37D, K55R, K70R, A71V, I72M, P79D |
| >CA59608| codons 1-99 PQITLWQRPIITIKVGGHIIEALLDTGADDTVLEEIDLPGRWKPKIIGGIGGFIRVRQYD QILIEICGHRVMGTVLVGDTPVNVIGRTLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219R | E6DN, K20R, T39E, E44D, V60I, V118VI, K122E, Q207E, D218E, E248D, A272AP, T286A, E297K, I326V | T131TI |
| >CA59609| codons 1-335 PISPINTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICEELEKDGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFIIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLWRWGFYTPERKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQG |
References
| Author | Title | Citation |
| Rhee, SY | Genotypic predictors of human immunodeficiency virus type 1 drug resistance. | PNAS, 2006 |