Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-A | ptAW44 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T | L24I | L10V, K20I, N37D, L63P, I66F, A71V, I72V |
| >ptAW44| 7 | codons 1-99 | clone 7 PQITLWQRPVVTIKIGGQLIKALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFVRVKQYD QIPIKICGHKVIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW44| 6 | codons 1-99 | clone 6 PQITLWQRPVVTIKIGGQLMEALIDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVRQYD QIPIEFCGHKVVGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW44| 5 | codons 1-99 | clone 5 PQITLWQRPVVTIKIGGQLMEALIDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVRQYD QIPIEICGHKVISTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW44| 4 | codons 1-99 | clone 4 PQITLWQRPVVTIKIGGQLMEALIDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVRQYD QIPIEFCGHKVVGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW44| 3 | codons 1-99 | clone 3 PQITLWQRPVVTIKIGGQLMEALIDTGADDTVLEKMDLPGRWKPKIIGGIGGFVKVRQYD QIPIEFCGHKVIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW44| 2 | codons 1-99 | clone 2 PQITLWQRPVVTIKIGGQLIEALIDTGADDIVLEEMDLPGRWKPKVIGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPTNIIGRNLLTQIGRTLNF >ptAW44| 1 | codons 1-99 | clone 1 PQITLWQRPVVTIKIGGQLMEALIDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPTNIIGRNLLTQIGCTLNF >ptAW44| codons 1-99 PQITLWQRPVVTIKIGGQLIEALIDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVRQYD QIPIEFCGHKVVGTVLVGPTPTNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |