Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA26324 | CA61104 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 18 |
| 2 | 3TC+AZT+IDV | 109 |
| 3 | 3TC+D4T+NFV | 291 |
| 4 | 3TC+NFV+TDF | 122 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70G, M184V | K43KN, E138A, I142T, S162C, K173KE, I178IM, L210LF, R211K, F214L, V245T, V261VG, A272P, V292I |
| >CA61104| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMENEGKISKIGPENPYNTPV FAIKKKDSTGWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSPAIFQCSMTKILEPFREQNPDMVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLFKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLGGKLNWASQIYPGIKVKQLCKLLRGTKALTEIIPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L33F, N88D | E35D, N37P, R57K, I62V, L63P, H69Q, A71T, V77VI |
| >CA61103| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADNTVFEDMPLPGRWKPKMIGGIGGFIKVKQYD QVPIEICGQKTIGTVLIGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |