Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-B | ptBW32 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L10I, K20M, E35D, M36I, R41K, L63P, A71T |
| >ptBW32| 12 | codons 1-99 | clone 12 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 11 | codons 1-99 | clone 11 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QILVEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 10 | codons 1-99 | clone 10 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 9 | codons 1-99 | clone 9 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 8 | codons 1-99 | clone 8 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 7 | codons 1-99 | clone 7 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 6 | codons 1-99 | clone 6 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 5 | codons 1-99 | clone 5 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 4 | codons 1-99 | clone 4 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 3 | codons 1-99 | clone 3 PQITLWQRPIVTIKIGGHLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QILVEICRHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| 1 | codons 1-99 | clone 1 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF >ptBW32| codons 1-99 PQITLWQRPIVTIKIGGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |