Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG347_0040 | 040_PR_w11 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+APV+AZT | 11 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37S, L63T, H69Y, K70KE, N98D |
| >040_PR_w11| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QITIEICGYEAIGTVLVGPTPVNIIGRNLLTQIGCTLDF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | E6ED, K32R, K49R, I50V, T165I, F214L | S68SC, P226S |
| >040_RT_w11| codons 1-233 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIRALVEICTEMEKEGKISRVGPENPYNTPV FAIKKKDCTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPSFLWMGYE |
References
| Author | Title | Citation |
| Murphy, RL | Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team. | J Infect Dis, 1999 |