<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-D ptDW36 U.S. 1995 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 36

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V   I13V, L63P, I64V, Q92L, I93L  
>ptDW36| 7 | codons 1-99 | clone 7
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTKLGCTLNF
>ptDW36| 6 | codons 1-99 | clone 6
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTKLGCTLNF
>ptDW36| 5 | codons 1-99 | clone 5
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTKLGCTLNF
>ptDW36| 4 | codons 1-99 | clone 4
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTKLGCTLNF
>ptDW36| 3 | codons 1-99 | clone 3
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGKNLMTQLGCTLNF
>ptDW36| 2 | codons 1-99 | clone 2
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTKLGCTLNF
>ptDW36| 1 | codons 1-99 | clone 1
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTKLGCTLNF
>ptDW36| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTILEEMNLPGRWKPKIVGGIGGFIKVRQYD
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTLLGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005