<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SM_02YE516 02YE516 Yemen 2002 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14N, L19Q, E35D, M36I, N37D, R41K, D60E, I62V, I64V  
>02YE516| codons 1-99
PQITLWQRPLVTINIGGQQKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYE
QVLVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35I, K49R, V60I, K122E, D123S, I135T, S162C, D177E, I178L, E204K, Q207E, F214L, V245T, E248Q, D250E, S251N, A272P, K281R, T286A, E291D, E297R, K311R, I329V, Y339W, A371V, T377Q, K390R, T403M, V435I, S468P, L469F, H483N, L491S, L517V, A554S  
>02YE516| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPELVI
YQYMDDLYVGSDLEIGQHRTKIEKLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPQKENWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDVIPLTREAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQGQGQWTWQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEVVQKIAQESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPFTDTTNQKTELQ
AINLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEVVSQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D6N, K7Q, E11D, E13D, L28I, L45Q, T112V, I113V, T124G, T125A, V201I, L234I, A265V S283G
>02YE516| codons 1-288
FLDGINQAQEDHDKYHSNWRAMASDFNIPPVVAKEIVASCDKCQQKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN
FTSGAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Saad, MD HIV type 1 strains common in Europe, Africa, and Asia co-circulate in Yemen. ARHR, 2005