<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NL_KHM_CD18 KHM_CD18 Cambodia 2004 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, E36D, T39K, K43E, K122E, D123N, T139S, S162C, K173T, Q174K, D177E, I178M, E194D, Q207N, L210M, R211K, K238R, V245E  
>KHM_CD18| codons 12-250
LKPGMDGPRVKQWPLTEEKIKALTDICKEMEEEGKISKIGPENPYNTPVFAIKKKDSTKW
RKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFT
IPSINNESPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTKNPEMVIYQYMDDLYVGS
DLDIGQHRTKIEELRNHLMKWGFTTPDKKHQKEPPFLWMGYELHPDRWTVQPIELPEKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, E35D, M36I, R41K, L63P, H69K, K70R, L89M  
>KHM_CD18| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Ly, N Characterization of mutations in HIV type 1 isolates from 144 Cambodian recently infected patients and pregnant women naive to antiretroviral drugs. ARHR, 2005