Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BB_92UG_029 | 92UG_029 | Uganda | 1992 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33F | I13V, E35D, M36I, R41K, K45R, R57K, Y59H, H69K, L89M |
| >92UG_029| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVFEDINLPGKWKPRMIGGIGGFIKVKQHD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, V35T, E40D, K49R, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, Q197K, T200A, Q207A, R211S, V245E, E248A, D250E, K275Q, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357K, G359S, T369A, A371V, I375V, A376T, T377M, A400T, T403R, E404D, E432D, L452Q, T470N, D471E, Q480H, H483Y, L491S, K512R, E516G, Q524K, K527E, E529D, A534S, A554S |
| >92UG_029| codons 1-560 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGKHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPAKESWTVNDIQKLVGKLNWASQIYAGIQVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVKQLAEVVQKVTMESIVIWGKTPKFKLPIQKETWETWWRDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRETKQGKAGYVTDRGRQKVVSLNETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESGLVSQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V32I, I72V, T112V, I113V, S119P, T124A, G134N, K136Q, V201I, N222K, L234I | S283G |
| >92UG_029| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGPN FTSATVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQKFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Brown, BK | Biologic and genetic characterization of a panel of 60 human immunodeficiency virus type 1 isolates, representing clades A, B, C, D, CRF01_AE, and CRF02_AG, for the development and assessment of candidate vaccines. | J Virol, 2005 |