Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA25596 | CA59468 | U.S. | 2005 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 48 |
| 2 | None | 126 |
| 3 | 3TC+AZT+NFV | 61 |
| 4 | None | 68 |
| 5 | 3TC+AZT+NFV | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | N37T, R41K, K43R, I62V, L63P, I64V, H69Y, V77I, Q92K, I93L |
| >CA59468| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMTLPGKWRPKIIGGIGGFIKVRQYD QVPVEICGYKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20R, D123E, I135T, I142V, A158AP, T200A, Q207H, F214L, R284K, I293V, E297K, K311R, Q334L, V365I, K390R, K395R, V435I, K451R, V466I, S468P, H483Y, Q547R |
| >CA59469| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPPIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRHHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKALTEVVPLTKEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARMRGA HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQRETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETRLGKAGYVTDRGRQKIVPLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNERVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |