Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-J | ptJW32 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F | L33I | L10I, Q18E, K20R, E35D, M36I, N37S, D60E, L63P, L89M, I93L |
| >ptJW32| 7 | codons 1-99 | clone 7 PQITPWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYE QIPIEICGHKAIGTVLVGPTPFNIIGRNMLTQLGCTLNF >ptJW32| 6 | codons 1-99 | clone 6 PQITLWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYD QIPIEICGHKAIGTVLVGPTPFNIIGRNMLTQLGCTLNF >ptJW32| 5 | codons 1-99 | clone 5 PQITLWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYD LIPIEICGHKAIGTVLVGPTPFNIIGRNMMTQLGCTLNF >ptJW32| 4 | codons 1-99 | clone 4 PQITLWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYE QIPIEICGHKAIGTVLVGPTPFNIIGRNMLTQLGCTLNF >ptJW32| 3 | codons 1-99 | clone 3 PQITLWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYE QIPIEICGHKAIGTVLVGPTPFNIIGRNMLTQLGCTLNF >ptJW32| 2 | codons 1-99 | clone 2 PQITLWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYE QIPIEICGHKAIGTVLVGPTPFNIIGRNMLTQLGCTLNF >ptJW32| codons 1-99 PQITLWQRPIVTIKIGGELREALLDTGADDTVIEDISLPGRWKPKMIGGIGGFVKVRQYE QIPIEICGHKAIGTVLVGPTPFNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |