<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL11977 73201 Portugal 2002 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ 3TC 682
2 None 13
3 AZT+ 3TC 169
4 AZT+ 3TC+ NFV 36

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, M184V D67G, K219Q     L34I, V35T, T39A, V60I, T69N, A98S, V111I, K122E, D123S, I135V, S162Y, Q174E, D177E, T200A, Q207K, R211S, F214L, V245Q, E248D, D250E, A272P, K277R  
>73201| codons 1-277
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKAITEICAELEKEGKISKIGPENPYNTPI
FAIKKKGSNRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDIGDAYFSVPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKENPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGLTTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   I13V, K14R, I15IV, K20T, E35D, M36I, R41K, I62V, H69K, A71T, T74S, V82I, L89I  
>73201| codons 1-99
PQITLWQRPLVTVRVGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVLIEICGKKTIGSVLVGPTPINIIGRNIMTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005