Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL865 | 70861 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC+ SQV | 256 |
| 2 | D4T+ 3TC+ SQV | 104 |
| 3 | AZT+ 3TC+ SQV | 60 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | V35T, K43R, V60I, T69TN, K122E, D123S, I135T, K173R, Q174K, D177E, T200A, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, R284RK, T286A, E291D, V292I, I293V, E297A, D324E, I329V |
| >70861| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGLTTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90MR | F53L | L10I, I13V, K14R, K20I, E35D, M36I, R41K, D60DE, L63AP, H69K, A71V, V82I, L89IM |
| >70861| codons 1-99 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGLVKVRQYE QIPIEICGKKVIGTVLVGPTPINIIGRNMRTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |