Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL55432 | 107397 | Portugal | 2004 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ NVP | 195 |
| 2 | 3TC+ TDF+ EFV | 67 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, M184V | K103N, M230L | V108I, F227FL | V35T, E36D, K49R, S68SG, K122N, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207G, H221Y, V245E, K275R, V276I, L283I, T286A, E291D, I293V, P294T, V317A, S322T, I326V |
| >107397| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISRIGPENPYNTPV FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DNDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTRNPEMVI YQYVDDLYVGSDLEIGQHRAKIEELRGHLLRWGFTTPDKKYQKEPPLLWLGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIRIKQLCKLIRGAKALTDVVTLTEEAE LELAENREILKEPVHGAYYDPTKDLVAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G17E, K20I, E35D, M36I, R41K, I64M, H69K, K70R, L89M |
| >107397| codons 1-99 PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |