Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL54810 | 105668 | Portugal | 2004 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ EFV | 225 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | P225H | V35T, E36D, I135V, S162T, Q174K, D177E, T200A, Q207EG, R211K, V245Q, T286A, E291D, V292I, I293V, P294A, S322T, I326V, K331N |
| >105668| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRKKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVALTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQNQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, K20I, M36I, R41K, G68E, H69K, K70R, L89M |
| >105668| codons 1-99 PQITLWQRPLVTVKIEGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICEKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |