Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL54063 | 103417 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ NVP | 47 |
| 2 | 3TC+ TDF+ NVP | 55 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, K70KE, M184V | K103KN, Y181C | V35T, K49R, V60I, A98S, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, T200V, Q207K, R211S, V245Q, E248D, D250E, A272P, V276VI, K277KR, T286A, A288AT, E291D, I293V, E297A, D320E, D324E, I329V |
| >103417| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKRKDSTEWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEIVI CQYVDDLYVGSDLEIGQHRVKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKTLTDVVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, Q18QR, K20I, E35D, M36I, R41K, H69K, V77I, V82I, L89M |
| >103417| codons 1-99 PQITLWQRPLVTVRIGGRLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLIGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |