<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL54063 103417 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDI+ NVP 47
2 3TC+ TDF+ NVP 55

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, Q18QR, K20I, E35D, M36I, R41K, H69K, V77I, V82I, L89M  
>103417| codons 1-99
PQITLWQRPLVTVRIGGRLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLIGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, K70KE, M184V   K103KN, Y181C   V35T, K49R, V60I, A98S, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, T200V, Q207K, R211S, V245Q, E248D, D250E, A272P, V276VI, K277KR, T286A, A288AT, E291D, I293V, E297A, D320E, D324E, I329V  
>103417| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKRKDSTEWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEIVI
CQYVDDLYVGSDLEIGQHRVKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKTLTDVVPLTAEAE
LELAENREILKEPVHGVYYEPSKELIAEVQKQG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005