<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL53865 102930 Portugal 2004 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ IDV 226
2 None 4
3 D4T+ 3TC+ EFV 56

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N, V106VM, Y188YH   P4S, V35T, E36D, W88C, K104KN, I135V, I142IV, S162A, K173I, Q174K, D177DEG, T200A, Q207E, R211K, F214L, V245Q, V276I, T286A, E291D, V292I, I293V, P294T, E297K, S322T E138EAPQ
>102930| codons 1-334
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNNSMTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNQTPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPGIVI
YQYMDDLHVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDIVTLTKEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K14R, G16E, L19P, K20V, M36I, R41K, H69K, L89M  
>102930| codons 1-99
PQITLWQRPVVTVRIEGQPVEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005