Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL53865 | 102930 | Portugal | 2004 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ IDV | 226 |
| 2 | None | 4 |
| 3 | D4T+ 3TC+ EFV | 56 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N, V106VM, Y188YH | P4S, V35T, E36D, W88C, K104KN, I135V, I142IV, S162A, K173I, Q174K, D177DEG, T200A, Q207E, R211K, F214L, V245Q, V276I, T286A, E291D, V292I, I293V, P294T, E297K, S322T | E138EAPQ |
| >102930| codons 1-334 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNNSMTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNQTPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPGIVI YQYMDDLHVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDIVTLTKEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, G16E, L19P, K20V, M36I, R41K, H69K, L89M |
| >102930| codons 1-99 PQITLWQRPVVTVRIEGQPVEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |