Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL53558 | 102179 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC+ NFV | 173 |
| 2 | D4T+ DDI+ NFV | 39 |
| 3 | D4T+ DDI+ ABC | 80 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69TADN, L210W, T215Y | V35T, K43R, V60I, A98S, K122E, D123S, I135IT, K173T, Q174K, D177E, T200A, E203EK, Q207QDEH, H208HY, R211K, L228LR, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, D324E, I329V |
| >102179| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISKIGPENPYNTPI FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIKELRHYLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, K20I, E35D, M36I, R41RK, I64IV, H69K, V82I, L89IM |
| >102179| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILVEICGKKAIGTVLVGPTPINIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |