<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL53431 101839 Portugal 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ TDF+ EFV 59

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62AV V106M, Y188C   V35T, K122E, K173A, D177E, I178L, E194EK, G196E, T200A, E204EG, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311R, D324E  
>101839| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPELVI
YQYVDDLCVGSDLKIEQHRAKIEGLREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILREPVHGVYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19V, M36I, R41K, D60E, Q61E, I62V, L63P, C67S, H69K, I93L  
>101839| codons 1-99
PQITLWQRPLVSIKIGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EVPIEISGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005