<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL52777 100126 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ TDF+ EFV 18

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR   L100I, K103N   V35T, V60I, A98S, D121H, K122E, S134SR, I135V, Q174E, D177E, I195K, T200A, V245Q, E248D, D250E, A272P, V276I, Q278H, L283I, T286A, E291D, V292I, I293V, E297A, D320E, D324E  
>100126| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGIKKNKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPRVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKENPEIVI
YQYMDDLYVGSDLEKGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKHLCKLIRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYEPSKELIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35D, M36I, R41K, K45R, H69K, V82I, L89M  
>100126| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005