Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL52393 | 99133 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ EFV | 64 |
| 2 | 3TC+ TDF+ EFV | 56 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T4S, L10I, I13V, G17E, K20I, E35D, M36I, R41K, L63M, H69K, V82I, L89M |
| >99133| codons 1-99 PQISLWQRPIVTVKIGEQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIMIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70E, M184V | K101P, K103N | E28EK, V35T, T39L, V60I, A98S, D121H, K122E, I135T, K173I, Q174K, T200A, Q207K, R211S, V245Q, E248D, D250EG, A272P, T286A, E291D, V292I, I293V, P294A, E297T, D320E, D324E, I329V | E29EG |
| >99133| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKGKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKDSTEWRKLVDFRELNKRTQDFWEVQLGIPHPSGLPKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKGSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVALTTEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |