<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL52389 99114 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ TDF+ EFV 17
2 3TC+ TDF+ EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V   K103N V179E E28K, V35T, K43R, V60I, S68SG, A98S, K102KR, K122E, D123S, I135T, T165I, K173I, Q174K, D177E, T200A, Q207E, H221Y, V245Q, E248D, D250E, A272P, T286A, A288AG, E291ED, V292I, I293IV, E297A, D320E, D324E, I329V  
>99114| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICTEMEREGKISKIGPENPYNTPI
FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKRNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRIKNPEIEI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKGLTDIVPLTAEAE
LELAENREILKEPVHGVYYEPSKELIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35D, M36I, R41K, C67S, H69K, V82I, L89M  
>99114| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005