Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL51786 | 97581 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC+ SQV | 291 |
| 2 | AZT+ DDI+ EFV | 69 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70R, T215F | D67GS, K219E | L100I, K103N | V35T, K43R, V60I, T69N, V90VI, A98S, K122E, I135T, K166KR, K173I, Q174K, D177G, T200A, E203EK, Q207EK, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V |
| >97581| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISKIGPENPYNTPI FAIKKKSSNRWRKLVDFRELNKRTQDFWEIQLGIPHPSGIKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPGIVI YQYMDDLYVGSDLEIGQHRAKIKELRKHLLSWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M |
| >97581| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |