<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL51339 96552 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ NFV 47
2 3TC+ TDF+ EFV 42

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75M Y188L   K32KN, V35T, K43R, V60I, V90I, K122E, D123N, I135T, S162H, F171Y, K173T, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, V292I, E297A, V317A, D324E K13KNT, L34LF
>96552| codons 1-333
PISPIETVPVKLTPGMDGPKVKQWPLTEEKINAFTEICTEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLMDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPYRTKNPEIVI
YQYVDDLLVGSDLEIGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIIPLTAEAE
LELAENREILKEPVHGAYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35D, M36I, L38LF, R41K, H69K, V82I, L89M  
>96552| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINFPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005