Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL50521 | 94398 | Portugal | 2004 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC | 21 |
| 2 | None | 21 |
| 3 | D4T+ 3TC+ NVP | 258 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | K103N, M230L | T7A, E28K, K32KE, V35T, T39DEKN, V118VI, D121H, I135T, I142V, S162C, K173A, Q174KR, D177E, G196D, T200A, Q207A, R211K, V245K, T286A, E291D, V292I, I293V, P294T, E297K, A304E, E312D |
| >94398| codons 1-334 PISPIEAVPVKLKPGMDGPKVKQWPLTKEKIEALTEICNEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL HKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPEIVI YQYVDDLYVGSDLEIDQHRAKIEELRAHLLKWGFFTPDKKHQKEPPFLWLGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTKEAE LELEENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, E35D, M36I, R41K, L63GISV, H69K, L89M, T91V, I93L |
| >94398| codons 1-99 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLVQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |